Gene content is curated by Tribro-Omics from published gene–disease evidence and checked against Human Phenotype Ontology gene annotations (release 2025-01-16). Inheritance and linked OMIM disorders in each panel come from HPO. Panels are reviewed by a clinical scientist before diagnostic use; genes in difficult regions (pseudogenes, repeat expansions, large deletions) are marked in each panel and may need an additional method. This product uses the Human Phenotype Ontology (hpo.jax.org).